Metabolic and cardiovascular effects of ghrelin

Metabolic and Cardiovascular Effects of Ghrelin

Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is synthesized as a preprohormone and then proteolytically processed to yield a 28-amino acid peptide. This peptide was originally reported to induce growth hormone release; large evidence, however, has indicated many other physiological activities of ghrelin, including regulation of food intake and energy balance, as w...

Impact of Ghrelin and Adiponectin on Metabolic and Cardiovascular Effects

Background: Ghrelin and adiponectin are recently discovered peptides. Ghrelin has a crucial role in the regulation of food intake and energy homeostasis, and adiponectin is secreted by adipocytes, and it has been proposed to mediate obesity-related insulin resistance. Both they are playing a critical role in a variety of physiological processes including endocrine, metabolic, cardiovascular, an...

Cardiovascular effects of ghrelin Doctoral Thesis

Ghrelin and Metabolic Surgery

Metabolic surgery is the most effective treatment for morbid obesity. Ghrelin has been implicated to play a role in the success of these procedures. Furthermore, these operations have been used to study the gut-brain axis. This article explores this interaction, reviewing the available data on changes in ghrelin levels after different surgical procedures.

Ghrelin and Cardiovascular Diseases

Ghrelin, a newly discovered bioactive peptide, is a natural endogenous ligand of the growth hormone (GH) secretagogue receptor and initially identified as a strong stimulant for the release of GH. Subsequent research has shown that ghrelin and its various receptors are ubiquitous in many other organs and tissues. Moreover, they participate in the regulation of appetite, energy, bodyweight, meta...